Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.273


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_1814297110.533.8e-17Click!
POU5F1chr6_-_311346140.171.3e-02Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_216241321 59.963 FN1
fibronectin 1
chr12_-_91573264 54.828 NM_133503
DCN
decorin
chr3_-_195310985 36.676 NM_001647
APOD
apolipoprotein D
chr1_-_93399531 30.104


chr3_-_195310770 29.956 APOD
apolipoprotein D
chr6_-_108145507 26.818 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr3_+_133494275 24.535 TF
transferrin
chr6_+_32407618 17.328 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr2_-_175712276 16.957 NM_001206602
CHN1
chimerin (chimaerin) 1
chr10_+_5005685 16.626 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr16_-_55867016 15.790 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr10_+_7745284 15.033 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745229 15.009 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_-_106733392 14.492 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr10_+_5005601 13.966 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_-_32497925 13.757 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr10_+_7745325 13.332 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_9920633 12.940 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr16_-_21314371 12.821 NM_001014444
NM_001888
CRYM

crystallin, mu

chr10_+_7745354 12.504 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_5005453 12.466 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_+_21264952 12.157 NM_182515
ZNF714
zinc finger protein 714
chr3_-_42305438 11.423 NM_001174138
CCK
cholecystokinin
chrX_+_135278912 11.219 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr4_-_15940362 11.147 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr1_-_177133950 10.965 NM_004319
NM_207108
ASTN1

astrotactin 1

chr10_-_5045967 10.812 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr14_-_106967528 10.670 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr8_+_39771327 10.277 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr17_-_79105747 10.216 NM_004920
AATK
apoptosis-associated tyrosine kinase
chr13_-_45048436 10.070 NM_001243798
TSC22D1
TSC22 domain family, member 1
chr1_-_24239758 10.039 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr8_-_120651019 9.703 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr5_+_140771482 9.683 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr4_-_70826712 9.410 NM_001891
CSN2
casein beta
chr12_+_7942025 9.318 NANOG
Nanog homeobox
chr8_-_82395401 9.118 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr14_-_107170400 8.975 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr5_+_140739589 8.804 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr15_+_25068793 8.789 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chrX_+_128913881 8.686 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_32582295 8.427 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr3_-_42917191 8.312 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr11_-_49229994 8.307 NM_001014986
NM_001193471
NM_001193472
NM_001193473
NM_004476
FOLH1




folate hydrolase (prostate-specific membrane antigen) 1




chr14_-_101036130 8.171 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr14_-_106774311 8.086 IGHA1
immunoglobulin heavy constant alpha 1
chr4_+_88720701 8.063 NM_004967
IBSP
integrin-binding sialoprotein
chr9_-_21350885 8.002 NM_021002
IFNA6
interferon, alpha 6
chr8_-_27115935 7.971 STMN4
stathmin-like 4
chr5_-_43412417 7.906 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr7_+_47694841 7.871 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr17_+_27369917 7.855 NM_016518
PIPOX
pipecolic acid oxidase
chr3_+_44666501 7.794 NM_001024855
NM_006991
ZNF197

zinc finger protein 197

chr2_-_224467142 7.698 NM_003469
SCG2
secretogranin II
chr5_+_173472692 7.581 NM_015980
HMP19
HMP19 protein
chr6_-_22297729 7.536 NM_000948
PRL
prolactin
chr14_-_106641585 7.521 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_38347426 7.508 NM_004803
SLC22A14
solute carrier family 22, member 14
chr16_+_72088507 7.451 NM_001126102
NM_005143
HP

haptoglobin

chr14_+_39703119 7.439 NM_054024
MIA2
melanoma inhibitory activity 2
chr13_-_28543290 7.405 NM_001265
CDX2
caudal type homeobox 2
chr3_-_38835500 7.404 NM_006514
SCN10A
sodium channel, voltage-gated, type X, alpha subunit
chr17_+_3379295 7.213 NM_000049
ASPA
aspartoacylase
chr2_+_74120132 7.201 ACTG2
actin, gamma 2, smooth muscle, enteric
chrX_+_128913897 7.172 SASH3
SAM and SH3 domain containing 3
chr12_+_133757994 7.059 NM_001165883
NM_001165884
NM_001165885
NM_001165886
NM_001165887
NM_003415
NM_152943
NM_001165881
NM_001165882
ZNF268








zinc finger protein 268








chr5_+_140729723 6.952 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr2_+_74120092 6.948 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr11_-_59633942 6.926 NM_001062
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr18_-_61329113 6.862 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr8_+_19796581 6.826 NM_000237
LPL
lipoprotein lipase
chr11_-_2152960 6.741 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_113885137 6.675 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr10_+_123754141 6.571 TACC2
transforming, acidic coiled-coil containing protein 2
chr4_+_70796798 6.521 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chrX_+_144908927 6.503 NM_004709
CXorf1
chromosome X open reading frame 1
chr18_-_3845295 6.363 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr4_+_100495972 6.335 MTTP
microsomal triglyceride transfer protein
chr4_+_154178525 6.238 TRIM2
tripartite motif containing 2
chr12_-_7656285 6.237 NM_004244
NM_203416
CD163

CD163 molecule

chr7_+_29519485 6.153 NM_001039936
CHN2
chimerin (chimaerin) 2
chr2_+_113885145 6.122 IL1RN
interleukin 1 receptor antagonist
chr5_-_997408 6.082 NM_001242737
LOC100506688
uncharacterized LOC100506688
chr9_-_13250313 6.057 NM_003829
MPDZ
multiple PDZ domain protein
chr2_+_90077732 5.925


chr15_+_25101697 5.909 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr19_+_58513428 5.848 LOC100128398
uncharacterized LOC100128398
chr17_+_3377346 5.819 NM_001128085
ASPA
aspartoacylase
chr7_+_37723378 5.809


chr2_-_89292396 5.771 IGKC
immunoglobulin kappa constant
chr5_-_58295758 5.765 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_163113938 5.750 RGS5
regulator of G-protein signaling 5
chr7_-_99680358 5.678 ZNF3
zinc finger protein 3
chr6_+_26156552 5.628 HIST1H1E
histone cluster 1, H1e
chr14_-_24423329 5.627 C14orf167
chromosome 14 open reading frame 167
chr3_+_156008775 5.588 NM_172159
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr19_+_7828034 5.483 NM_001144904
NM_001144905
NM_001144906
NM_001144907
NM_001144908
NM_001144909
NM_001144910
NM_001144911
NM_014257
CLEC4M








C-type lectin domain family 4, member M








chr17_+_27370155 5.464 PIPOX
pipecolic acid oxidase
chr9_-_21187529 5.337 NM_021068
IFNA4
interferon, alpha 4
chr17_-_67138013 5.327 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr8_-_27115897 5.316 NM_030795
STMN4
stathmin-like 4
chr2_-_224467095 5.272 SCG2
secretogranin II
chr18_+_46065367 5.248 NM_001142397
NM_014772
CTIF

CBP80/20-dependent translation initiation factor

chr12_+_7941994 5.199 NM_024865
NANOG
Nanog homeobox
chr9_+_6215785 5.180 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr13_+_23755059 5.034 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_-_10021932 5.030 CLEC2B
C-type lectin domain family 2, member B
chr5_+_140809957 4.968 PCDHGA12
protocadherin gamma subfamily A, 12
chr9_+_97488993 4.915 C9orf3
chromosome 9 open reading frame 3
chr11_+_5710816 4.859 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr2_+_207406815 4.821 ADAM23
ADAM metallopeptidase domain 23
chr6_+_27833033 4.799 NM_003511
HIST1H2AI
HIST1H2AL
histone cluster 1, H2ai
histone cluster 1, H2al
chr7_+_142560512 4.773 EPHB6
EPH receptor B6
chr4_+_69313166 4.705 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr6_+_26156558 4.641 NM_005321
HIST1H1E
histone cluster 1, H1e
chr1_-_160492982 4.593 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr2_-_166060552 4.582 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr12_-_102874299 4.560 IGF1
insulin-like growth factor 1 (somatomedin C)
chr2_-_89442551 4.520 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr14_+_69658215 4.495 EXD2
exonuclease 3'-5' domain containing 2
chrX_+_83116153 4.446 NM_021118
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr18_-_28622624 4.437 NM_001941
NM_024423
DSC3

desmocollin 3

chr5_-_64777703 4.367 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr17_-_29641068 4.353 EVI2B
ecotropic viral integration site 2B
chr6_+_26045611 4.340 NM_003531
HIST1H3C
histone cluster 1, H3c
chr3_+_148447966 4.340 NM_032049
AGTR1
angiotensin II receptor, type 1
chr1_-_150552077 4.333 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr3_+_159557745 4.297 SCHIP1
schwannomin interacting protein 1
chr12_-_21487831 4.284 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr17_-_46608271 4.272 NM_002144
HOXB1
homeobox B1
chr11_-_118047145 4.270 SCN2B
sodium channel, voltage-gated, type II, beta
chr6_-_22303014 4.193 NM_001163558
PRL
prolactin
chrY_-_2655478 4.139 NM_003140
SRY
sex determining region Y
chr17_-_64225496 4.122 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr11_-_73720281 4.100 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr1_+_101185195 4.059 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr3_+_108021331 4.056 NM_007072
HHLA2
HERV-H LTR-associating 2
chr7_-_137028370 4.005 PTN
pleiotrophin
chr14_-_107066061 4.000 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_+_79330990 3.980 NM_003248
THBS4
thrombospondin 4
chr3_-_123603144 3.963 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr5_+_140254930 3.936 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr3_-_155421996 3.889 NM_014996
PLCH1
phospholipase C, eta 1
chrX_+_91090459 3.880 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr19_-_5838740 3.830 FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr7_-_8302141 3.787 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr14_+_69658193 3.783 NM_001193360
NM_001193361
NM_018199
EXD2


exonuclease 3'-5' domain containing 2


chr3_+_153838791 3.767 NM_001251962
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr10_+_7745341 3.751 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr16_-_21663908 3.650 IGSF6
immunoglobulin superfamily, member 6
chr7_+_1126442 3.643 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chrX_-_55020510 3.637 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_-_11091805 3.635 NM_023922
TAS2R14
taste receptor, type 2, member 14
chr14_-_106725620 3.608 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_131958441 3.578 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr2_-_21225640 3.577 APOB
apolipoprotein B (including Ag(x) antigen)
chr10_-_69597768 3.567 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr9_+_2717525 3.556 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr5_+_173472737 3.551 HMP19
HMP19 protein
chr6_-_116601085 3.544 TSPYL1
TSPY-like 1
chr14_-_106967080 3.526 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_101112548 3.517 NM_032946
NXF5
nuclear RNA export factor 5
chr20_-_1472168 3.506 NM_001122962
NM_001134836
SIRPB2

signal-regulatory protein beta 2

chr9_-_21166609 3.485 NM_002175
IFNA21
interferon, alpha 21
chr14_-_106452693 3.476 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106721450 3.465


chr12_-_8815370 3.451 NM_003480
MFAP5
microfibrillar associated protein 5
chr13_-_110802708 3.438 COL4A1
collagen, type IV, alpha 1
chr6_+_131894343 3.420 NM_000045
NM_001244438
ARG1

arginase, liver

chr18_+_29171729 3.417 NM_000371
TTR
transthyretin
chr1_+_87012758 3.403 NM_012128
CLCA4
chloride channel accessory 4
chr2_+_138721807 3.393 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr1_-_120311466 3.386 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr12_+_130647002 3.382 NM_007197
FZD10
frizzled family receptor 10
chr10_-_52645430 3.380 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr12_-_14996381 3.288 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr11_+_5710926 3.258 TRIM22
tripartite motif containing 22
chr10_+_114133775 3.257 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_42259397 3.187 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr1_+_162602198 3.172 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chrX_+_2958274 3.155 NM_001201538
ARSF
arylsulfatase F
chrX_-_54069593 3.130 NM_001184898
PHF8
PHD finger protein 8
chr13_-_36429798 3.126 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr1_+_32050510 3.119 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_112938799 3.100 NM_018704
CTTNBP2NL
CTTNBP2 N-terminal like
chr5_-_135290521 3.085 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr22_+_23063107 3.084 IGLJ3
immunoglobulin lambda joining 3
chr14_-_107259620 3.054 IGHV5-78
immunoglobulin heavy variable 5-78 (pseudogene)
chr11_+_69455884 3.049 CCND1
cyclin D1
chr4_-_176733413 3.030 GPM6A
glycoprotein M6A
chr1_-_177133818 2.999 ASTN1
astrotactin 1
chr7_+_80267922 2.991 CD36
CD36 molecule (thrombospondin receptor)
chr3_+_159557649 2.949 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr1_+_163038934 2.944 NM_001113381
RGS4
regulator of G-protein signaling 4
chr9_+_124048396 2.925 GSN
gelsolin
chr8_+_12869772 2.871 NM_001099677
KIAA1456
KIAA1456
chr12_-_102874321 2.866 IGF1
insulin-like growth factor 1 (somatomedin C)
chr15_-_78526841 2.866 NM_001199377
NM_015162
ACSBG1

acyl-CoA synthetase bubblegum family member 1

chr14_-_106453162 2.839 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_+_94577078 2.811 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.85 2.79e-09 GO:0006955 immune response
2.36 3.12e-09 GO:0002376 immune system process
1.42 1.15e-07 GO:0050896 response to stimulus
1.86 1.46e-05 GO:0007166 cell surface receptor linked signaling pathway
1.52 5.86e-05 GO:0023052 signaling
1.48 6.68e-05 GO:0051716 cellular response to stimulus
2.30 9.65e-05 GO:0006952 defense response
1.54 1.29e-04 GO:0007165 signal transduction
2.93 4.51e-04 GO:0045087 innate immune response
4.07 8.01e-04 GO:0009615 response to virus
2.50 8.42e-04 GO:0007186 G-protein coupled receptor protein signaling pathway
2.23 1.10e-03 GO:0007155 cell adhesion
2.23 1.10e-03 GO:0022610 biological adhesion
2.74 1.15e-03 GO:0051707 response to other organism
1.63 1.31e-03 GO:0042221 response to chemical stimulus
8.42 1.35e-03 GO:0008206 bile acid metabolic process
6.24 2.04e-03 GO:0001959 regulation of cytokine-mediated signaling pathway
2.25 2.08e-03 GO:0002682 regulation of immune system process
2.05 2.26e-03 GO:0070887 cellular response to chemical stimulus
6.14 2.42e-03 GO:0060759 regulation of response to cytokine stimulus
9.23 2.62e-03 GO:0060338 regulation of type I interferon-mediated signaling pathway
1.16 2.63e-03 GO:0009987 cellular process
1.69 2.76e-03 GO:0048583 regulation of response to stimulus
3.32 2.79e-03 GO:0008202 steroid metabolic process
2.48 3.02e-03 GO:0009607 response to biotic stimulus
7.60 3.44e-03 GO:0031214 biomineral tissue development
1.35 3.55e-03 GO:0032501 multicellular organismal process
2.04 3.97e-03 GO:0009611 response to wounding
1.97 8.31e-03 GO:0006629 lipid metabolic process
15.73 1.34e-02 GO:0010660 regulation of muscle cell apoptosis
5.58 1.77e-02 GO:0060337 type I interferon-mediated signaling pathway
5.58 1.77e-02 GO:0071357 cellular response to type I interferon
5.49 2.05e-02 GO:0034340 response to type I interferon
5.99 2.72e-02 GO:0006109 regulation of carbohydrate metabolic process
5.99 2.72e-02 GO:0010675 regulation of cellular carbohydrate metabolic process
2.71 2.79e-02 GO:0032787 monocarboxylic acid metabolic process
2.27 3.46e-02 GO:0008284 positive regulation of cell proliferation
2.73 3.75e-02 GO:0016337 cell-cell adhesion
3.70 4.52e-02 GO:0007156 homophilic cell adhesion
2.35 4.74e-02 GO:0050776 regulation of immune response
1.22 4.97e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.16 3.56e-14 GO:0005576 extracellular region
2.68 9.04e-13 GO:0044421 extracellular region part
2.93 3.60e-12 GO:0005615 extracellular space
1.62 2.01e-10 GO:0005886 plasma membrane
1.61 3.79e-10 GO:0071944 cell periphery
1.89 4.33e-09 GO:0044459 plasma membrane part
2.24 7.36e-09 GO:0005887 integral to plasma membrane
2.20 1.78e-08 GO:0031226 intrinsic to plasma membrane
1.89 1.24e-02 GO:0005626 insoluble fraction
1.90 1.25e-02 GO:0005624 membrane fraction
2.37 1.50e-02 GO:0009986 cell surface
1.27 1.77e-02 GO:0031224 intrinsic to membrane
1.21 1.87e-02 GO:0016020 membrane
1.23 4.01e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.82 2.10e-05 GO:0004872 receptor activity
1.72 2.42e-05 GO:0004871 signal transducer activity
1.72 2.42e-05 GO:0060089 molecular transducer activity
4.14 6.71e-05 GO:0001871 pattern binding
4.14 6.71e-05 GO:0030247 polysaccharide binding
3.57 3.54e-04 GO:0005125 cytokine activity
1.87 3.58e-04 GO:0004888 transmembrane receptor activity
2.66 1.11e-03 GO:0030246 carbohydrate binding
4.37 1.47e-03 GO:0008201 heparin binding
1.89 3.18e-03 GO:0005102 receptor binding
6.92 5.95e-03 GO:0003823 antigen binding
3.53 9.10e-03 GO:0005539 glycosaminoglycan binding
17.30 1.66e-02 GO:0005132 interferon-alpha/beta receptor binding
3.08 2.68e-02 GO:0005126 cytokine receptor binding
25.96 3.53e-02 GO:0047023 androsterone dehydrogenase activity
25.96 3.53e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity